This book features research papers presented at the International Conference on Data Mining and Information Security (ICDMIS 2025) held in Phnom Penh in collaboration with Eminent College of Management & Technology (ECMT) and University of Puthisastra, Cambodia, during October 7–8, 2025. The book is organized in five volumes and includes high-quality research work by academicians and industrial experts in the field of computing and communication, including full-length papers, research-in-progress papers, and case studies related to all the areas of data mining, machine learning, Internet of Things (IoT), and information security.