Mathematics in Science and Technology Innovation is a comprehensive textbook showcasing how mathematics underpins progress across science and technology disciplines. Spanning ten systematically organized chapters, this resource explores fundamental connections between mathematical theory and practical innovation. The text is designed for undergraduate students globally, beginning with core mathematical principles and advancing to complex applications in contemporary scientific and technological contexts. Content avoids regional limitations, instead highlighting universally relevant cases and innovative applications. Readers examine mathematical modeling, computational methods, optimization techniques, and analytical approaches essential for scientific research and technological development. Key topics include differential equations in physical systems, statistical methods in data science, numerical analysis for engineering problems, and discrete mathematics for computer science applications. The book demonstrates how mathematics enables breakthroughs in fields including physics, chemistry, biology, engineering, and information technology. Through carefully selected examples and structured pedagogy, the material builds student capability to apply mathematical tools creatively in diverse innovation contexts. This resource serves students, educators, and professionals seeking deep understanding of mathematics as the foundational language of science and technology. The text balances theoretical rigor with practical relevance for modern applications.